Specialty Reactions

Iodination Technology

By leveraging a wide range of iodinating agents, we can provide the iodine compounds you require

Iodination with an iodinating reagent *1

*1: JP2008-2854473, WO2008/143141

Iodination with iodine and an oxidizing agent

Sandmeyer reaction

Bromination Technology

We also specialize in bromination, leveraging the expertise we have developed in iodination

Bromination with bromine

Bromination with hydrogen bromide

Production of brominated lactones *2

*2: JP5837752

Cyanation Technology

By leveraging a wide range of cyanating agents, we can provide the cyanide derivatives and derivatives you require

Cyanation via halogen–cyano exchange

Sandmeyer reaction

Cyanation using cyanogen halides

Synthesis of cyanohydrin compounds *3

*3: JP4822764, JP4782436, WO2007/018221, WO2009/054356

Asymmetric cyanohydrin formation of aromatic aldehydes *4

*4: JP4822764, JP4782436, WO2007/018221, WO2009/054356

Strecker reaction

Synthesis of ortho ester compounds

Synthesis of amidine compounds from cyano compounds

Synthesis of amidine compounds from ortho esters

Synthesis of azo compounds

Other Derived Technologies

We also have an extensive track record in organic and inorganic synthesis
We also welcome inquiries about reactions not listed here. Please feel free to contact us.

Coupling Reactions

Suzuki-Miyaura Coupling

Sonogashira Coupling

Synthesis of aromatic secondary amines using a Pd catalyst *5

*5: JP3989249, JP2008308413A

Synthesis of aromatic tertiary amines using a Pd catalyst *6

*6: JP3989249, JP2008308413A

Epoxidation and Methylenation

Example Epoxidation and methylenation with TMSOI

Methylation

Example Methylation with methyl iodide

Hypervalent iodine

Example Diaryliodonium salt

Example Iodobenzene diacetate